Abstract aim: study women response during and post their first gynecological examination. Setting: The study was conducted at the gynecological clinic at Αin-Shams University Maternity Hospital. Subjects/methods: Α descriptive study design. Sampling: Sample size was 199 from females who attended to the previously mentioned study setting for the first time. Sample type: Α purposive sample. Tools: four tools of data collection were used. I: Α Structured interviewing questionnaire; II: The emotional situational nonverbal response questionnaire; III: The situational verbal response checklist; IV: The visual analogue scale to assess pain level. Results: The present study results had revealed that the majority of the studied sample reported that gynecological examination was а stressful event. Conclusion: the present study concluded that the most of women corresponding with negatively verbal and nonverbal emotional response as well as the majority were an embarrassment. First gynecological examination was а stressful event, and it was immoral to expose intimate part. Recommendation: design guideline, and poster concerning the importance and technique of female gynecological examination.